Treating Brain Injury with Stem Cell Therapy

What Is a Stem Cell?

Basically a “blank” cell, an adult stem cell is capable of becoming another cell type in the body, such as a skin cell, a muscle cell, or a nerve cell. Adult stem cell therapy can be administered to help replace or even heal damaged tissues and cells, serving as a built-in repair system for the human body and replenishing other cells.Recent stem cell research by the University of Texas Health Science Center at Houston (UTHealth) suggests that this cellular therapy can help reduce neuroinflammation, preserve brain tissue and improve cognitive function following traumatic brain injury (TBI). Meanwhile, other studies have indicated that adult neural stem cells have regenerative and reparative properties for the treatment of injuries or diseases in the central nervous system.
By definition, stem cells are undifferentiated biological cells that can differentiate into specialized cells and divide to produce more stem cells. There are three ways adult stem cells can be obtained: from bone marrow, adipose tissue, or blood.
Unlike embryonic stem cells, the use of adult stem cells in research and therapy is not considered to be controversial, as they are derived from adult tissue samples rather than discarded human embryos. By law, these adult stem cells have to be injected or infused into the patient within 24 hours after being obtained.**Results may vary; no guarantee of specific results

What are the Different Types of Stem Cells?

Multipotent adult stem cells, those derived from bone or adipose tissue, have the ability to divide and generate all cell types of the organ from which they originate. They possess two properties: self-renewal and multi-potency, meaning they can go through numerous cycles of cell division while still maintaining their undifferentiated state. Pluripotent adult stem cells, those derived from the blood, have the ability to divide and generate all cell types and are consider “uncommitted”. These stem cells hold the ability to generate into several distinct cell types, including neural cells found in the brain. Pluripotent stem cells behave like embryonic stem cells and give rise to all the cell types in the body. They endure a long lifespan and work best in combination with PRP. TBI Therapy only uses pluripotent stem cells in efforts to obtain the best results possible! Regenerative stem cell therapy can stimulate tissue re-growth and greater blood flow to the affected areas.* The goal of treatment with stem cells is to replace damaged cells and to promote the growth of new blood vessels and tissues in order to help the target organ function at a greater capacity.* *Results may vary; no guarantee of specific results

Amniotic stem cells:

Amniotic fluid is what surrounds the baby. When the mother’s water breaks, this is the fluid that ends up on the floor. While amniotic fluid likely contains helpful growth factors and some “extracellular matrix,” it is not a stem cell product. See

Umbilical stem cells:

Most umbilical cells are not pluripotent but multipotent.  There are currently several limitations to using Umbilical Cord stem cells. Although many different kinds of multipotent stem cells have been identified, Umbilical Cord stem cells that could give rise to all cell and tissue types have not yet been found. See:


Be cautious about using cord blood or amniotic cells from another person due to widespread environmental contamination. Maternal exposure to some PFAS has been linked to altered thyroid hormone levels in maternal and umbilical cord blood. Chemicals designed to repel oil and water, known as PFAS (per- and polyfluoroalkyl substances), have been used widely in everything from food wrappers, cosmetics, and textiles, to firefighting foams. As a result, they have been detected into our food, water and our bodies.

Most forms of regenerative medicine are still in early stages of development and adult stem cells and stem cells from birthing tissues have not yet been shown to be safe and effective for use in the treatment of any other diseases or conditions.

The FDA issued a warning letter to Cord for Life, Inc., located in Altamonte Springs, Florida, for manufacturing unapproved umbilical cord blood products in violation of current good manufacturing practice (CGMP) requirements, including failing to validate processes to prevent bacterial contamination, raising potential significant safety concerns that put patients at risk. In addition, the FDA issued 20 letters to separate manufacturers and health care providers across the country who may be offering unapproved stem cell products, reiterating the FDA’s compliance and enforcement policy.


“I don’t think the umbilical stems did anything, it was a couple of years ago.

I also heard a podcast and the doc said all the umbilical cells are dead.”

-patient report

What to Know Before Getting Stem Cells

Dr. Hughes presents about the various types of stem cells and what they are best used for including: adult vs embryonic, pluripotent vs multipotent, and blood-based vs. mesenchymal.

Stem Cells for TBI

Join Dr. Hughes during his LIVE webinar as he talks about the benefits of intranasal adult stem cells for the treatment of traumatic brain injury.

“Three months after my first stem cell procedure at TBI Therapy, I felt well enough to travel for the first time since going down with my symptoms. My light and sound sensitivity had reduced, and my mood was improving.”

Intranasal Stem Cell Procedure

Stem cells are harvested from the patient’s blood by a simple blood draw typically 6-12 hours before they are infused. During infusion, the patient will lay back on the exam table with their head tilted perpendicular to the ground. After local anesthetic is sprayed into the nose, the cells are dripped up the nose with a special device. The patient will lie there for another 15 minutes while the cells fuse into the brain. After this, the patient is free to get up and continue their daily activities.

To promote optimal regeneration, stem cell infusions are usually paired with several hyperbaric oxygen therapy (HBOT) sessions before and after. Intranasal PRP is also infused the day before stem cells to enhance the regeneration process.

“In June 2017, I went in for my second intranasal stem cell procedure and by August I felt well enough that I started saying yes again to facilitating events and speaking gigs. I also experienced relief from anxiety. With the stem cell procedures, the results were never immediate but 8-12 weeks post procedure I experienced a noticeable jump in my healing. Even though, I’m still not 100% back to what I was, TBI Therapy has turned me into a TBI THRIVER, not just a survivor. I’m happy. I enjoy life again, can travel and am doing work in the world that’s more aligned with myself than ever.”

Stem Cell Technology Used at TBI Therapy

The stem cells are extracted using the Tithon Biotech technology. This patented procedure termed PBD-PSC Technology, is founded in discoveries involving a unique population of pluripotent stem cells. These cells were initially isolated from adipose-tissue (fat), but were later found to originate in bone marrow and distributed in peripheral blood as well as other body fluids. These cells are in abundance in peripheral blood and in reproductive tissue secretions and dissipate in number and function in humans as they age. Tithon Biotech scientists have determined that these cells play a large role in future stem cell based therapeutic applications in both humans and animals.

Tithon Studies

Tithon- Pseudarthrosis Case Study

Tithon- Osteoporosis Case Studies

Tithon- The Efficacy and safety of an autologous fractionated plasma extract (PDSC-PRP) on skin rejuvenation

“Traditionally, inflammation continues to be considered a natural, but sometimes harmful, response to injury, inch said Helen Blau, PhD, professor of microbiology plus immunology and director of Stanford’s Baxter Laboratory intended for Stem Cell Biology. “But we wondered whether there can be a component in the pro-inflammatory signaling cascade that also activated muscle repair. We found that a single exposure to prostaglandin E2 has a profound effect on the proliferation of muscle tissue stem cells in living animals. We postulated that individuals could enhance muscle regeneration by simply augmenting this organic physiological process in existing stem cells already situated along the muscle fiber.”